Every word he uttered, every thing he wrote, everywhere he went, the Apostle Paul was a living witness of total surrender to His Lord. He wasn't perfect, but he didn't allow personal problems to hinder the Lord's work.
When nothing else matters in your life but what matters to God, His work will get done.
Romans 12:1 I beseech you therefore, brethren, by the mercies of God, that ye present your bodies a living sacrifice, holy, acceptable unto God which is your reasonable service.
2. And be not conformed to this world, but be ye transformed by the renewing of your mind, that ye may prove what is that good and acceptable and perfect will of God.
Is your life totally committed to God? Do you eagerly anticipate doing His will? Those who need to hear the Gospel are running out of time. One day our lives will end. We must bear fruit for Jesus while we can.